Psychological / emotional perspective: For an epidemic / plague to take hold people would need to be capable of being contaminated. From an emotional perspective in dreams an epidemic might suggest some kind of group hysteria.... Dream Meanings of Versatile
1- In olden times, plague and pestilence was believed to come from an angry God. In fact, most plagues are caused by an imbalance in natural ecology.
To dream of a plague will highlight some internal imbalance within ourselves. This may be physical, emotional, mental or spiritual. One quality of a plague, no matter what it is, is that there is too much. We can be overwhelmed by it, as happened with the plague of locusts chronicled in the Bible.
2- One outstanding example of a plague in the Bible was that of Job who was plagued by boils. This suggests the old-fashioned idea that if one did not conform, retribution would occur.
To dream of a plague, therefore, is to recognise that we will suffer if we do not attempt to reach our highest potential.
3- In spiritual terms a plague signifies Divine Retribution.... Ten Thousand Dream Dictionary
An alternative type of judgment dream. Many ancient cultures regarded widespread sickness as a sign of divine displeasure.
Blights perceived as being on your soul or spirit, like a curse.
Bitterness that rots away inside, creating all manner of dis-ease.
AIDS: In literal terms, AIDS is the plague of the 21st century, so this dream may express an honest fear playing itself out, or a homophobic reaction.
Leprosy: Feeling like your life is falling apart a little at a time, or that you are slowly losing yourself to someone or something. Alternatively, an experience or action that makes you feel “unclean” (see Din).
What or who does the plague affect? The answer to this question can reveal one’s anger, moral conflict, or prejudice pertaining to a group, person, or situation.... The Language of Dreams